Thermal fatigue and oxidation data on TAZ-8A, MAR-M 200, and Udimet 700 superalloys

The fluidized bed technique was used to determine the relative thermal fatigue and oxidation resistance of three superalloys: TAZ-8A, Mar-M 200, and Udimet 700. The alloys TAZ-8A and MAR-M 200 were also tested in the directionally-solidified form. For the 13 combinations of composition, solidification method, surface protection, and specimen geometry, the cycles to cracking varied from 1250 to 15,000. The alloy/coating having the best resistance to thermal fatigue cracking was coated directionally-solidified NASA TAZ-8A. This combination also had excellent oxidation resistance

Loudness (annoyance), prediction procedure for steady sounds

Method has been devised to predict loudness level of any steady sound solely from its measured power spectrum level. Method is based on assumption that, with respect to loudness sensation, the human auditory system acts as open-loop transmission system with transmittance function determined from measured tone curves

Analytical model for determining spacecraft impact velocity and orientation relative to an impact surface

Development of analytical model for determining spacecraft impact velocity and orientation relative to impact surface for variable dynamic condition

Imagining inclusive teachers: contesting policy assumptions in relation to the development of inclusive practice in schools

In this paper we reflect on data from two research projects in which inclusive practice in schools is at issue, in the light of wider field experience (our own and others’) of school and teacher development. We question what we understand to be relatively common, implicit policy assumptions about how teachers develop, by examining the way in which teachers are portrayed and located in these projects. The examples discussed in this paper draw on experience in Lao PDR and Bangladesh, critically exploring teachers’ roles, position and agency in practice. Similarities and differences rooted in cultural, political and institutional contexts highlight in a very productive way the significance and potential dangers of policy assumptions about teachers within the process of development. In Bangladesh, a success story is presented: the case of a group of schools in which an institutional context for learning appears to sustain teachers’ commitment and motivation, with the effect of creating meaningful outcomes for young people who were previously outside the education system. These data raise questions about the significance of institutional context to teachers’ practices, and questions about approaches to teacher development which omit consideration of that context by, for example, focusing inadvertently on features of individual teachers. We then consider teachers’ responses to the movement for inclusive education in a school in the Lao PDR since 2004. Inclusion here was understood to require a significant shift in teacher identity and a movement away from authoritative pedagogy towards the facilitation of a pedagogy which aimed to encourage the active participation of all students. Through a longitudinal study of teachers in one school, the conditions for such change were identified and again cast doubt on some of the assumptions behind large-scale attempts at teacher development. Reflecting on these experiences and the evidence they provide, we suggest that teacher development programmes are more likely to be effective where teachers are considered not as individuals subject to training but as agents located in an influential institutional context

Polarized Neutron Matter: A Lowest Order Constrained Variational Approach

In this paper, we calculate some of the polarized neutron matter properties, using the lowest order constrained variational method with the $AV_{18}$ potential and employing a microscopic point of view. A comparison is also made between our results and those of other many-body techniques.Comment: 23 pages, 8 figure

An amplification-free ultra-sensitive electrochemical CRISPR/Cas biosensor for drug-resistant bacteria detection.

Continued development of high-performance and cost-effective diagnostic tools is vital for improving infectious disease treatment and transmission control. For nucleic acid diagnostics, moving beyond enzyme-mediated amplification assays will be critical in reducing the time and complexity of diagnostic technologies. Further, an emerging area of threat, in which diagnostics will play an increasingly important role, is antimicrobial resistance (AMR) in bacterial infections. Herein, we present an amplification-free electrochemical CRISPR/Cas biosensor utilizing silver metallization (termed E-Si-CRISPR) to detect methicillin-resistant (MRSA). Using a custom-designed guide RNA (gRNA) targeting the gene of MRSA, the Cas12a enzyme allows highly sensitive and specific detection when employed with silver metallization and square wave voltammetry (SWV). Our biosensor exhibits excellent analytical performance, with detection and quantitation limits of 3.5 and 10 fM, respectively, and linearity over five orders of magnitude (from 10 fM to 0.1 nM). Importantly, we observe no degradation in performance when moving from buffer to human serum samples, and achieve excellent selectivity for MRSA in human serum in the presence of other common bacteria. The E-Si-CRISPR method shows significant promise as an ultrasensitive field-deployable device for nucleic acid-based diagnostics, without requiring nucleic acid amplification. Finally, adjustment to a different disease target can be achieved by simple modification of the gRNA protospacer. [Abstract copyright: This journal is © The Royal Society of Chemistry.

Concepts and procedures used to determine certain sea wave characteristics

A technique and its application are presented by which wave parameters, critical to spacecraft water impact load analysis, may be determined